Revelation 9:15

So the four angels, who had been prepared for the hour and day and month and year, were released to kill a third of mankind.

·         The time of their military operations is limited (MH)

·         The Euphrates was a landmark of ancient Babylon. It was the frontier of the Israel’s land as fully promised by God (Genesis 15:17-21). It was also the boundary of the old Roman Empire, which will be revived under the Antichrist. (DG)

·         The Euphrates is also associated with the first sin (Genesis 2:10-14), the first murder (Genesis 4:16), the first organized revolt against God (Genesis 11:1-9), the first war confederation (Genesis 14:1), and the first dictatorship (Genesis 10:8-10). (DG)